Open AccessBORTEZOMIB EXHIBITS THERAPEUTIC IMPLICATION IN RENAL INTERSTITIAL FIBROSIS AFTER KIDNEY TRANSPLANTATION BY INHIBITING AKT-MTOR-P70S6K-SMURF2 PATHWAY AND STABILIZING IΚBΑ PROTEIN
Author(s) -
Chuanjian Suo,
Hao Chen,
Liguang Sun,
Zijie Wang,
ZeGuang Han,
Jun Tao,
Xingrong Ju,
Ruoyun Tan,
Min Gu
Publication year - 2020
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/01.tp.0000699072.47861.bc
Subject(s) - bortezomib , cancer research , epithelial–mesenchymal transition , protein kinase b , transplantation , medicine , pi3k/akt/mtor pathway , fibrosis , kidney , proteasome inhibitor , signal transduction , chemistry , pathology , biology , multiple myeloma , microbiology and biotechnology , cancer , metastasis