Open AccessSection 1. Image Evaluation of Fatty Liver in Living Donor Liver Transplantation
Author(s) -
YuFan Cheng,
ChunYen Yu,
HsinYou Ou,
Leo Leung-Chit Tsang,
TienHung Huang,
Tai-Yi Chen,
Allan M. Concejero,
Chih-Chi Wang,
Shih-Ho Wang,
TsanShiun Lin,
YuehWei Liu,
ChienHsin Yang,
Chee-Chien Yong,
King-Wah Chiu,
Bruno Jawan,
HockLiew Eng,
ChaoLong Chen
Publication year - 2014
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/01.tp.0000446265.42019.f3
Subject(s) - steatosis , liver transplantation , medicine , fatty liver , living donor liver transplantation , hepatectomy , magnetic resonance imaging , transplantation , ultrasonography , clinical imaging , sampling (signal processing) , radiology , surgery , pathology , computer science , computer vision , disease , resection , filter (signal processing)
Preoperative evaluation of donors for living-donor liver transplantation aims to select a suitable donor with optimal graft quality and to ensure donor safety. Hepatic steatosis, a common finding in living liver donors, not only influences the outcome of liver transplantation for the recipient but also affects the recovery of the living donor after partial hepatectomy. Histopathologic analysis is the reference standard to detect and quantify fat in the liver, but it is invasive, and results are vulnerable to sampling error. Imaging can be repeated regularly and allows assessment of the entire liver, thus avoiding sampling error. Selection of appropriate imaging methods demands understanding of their advantages and limitations and the suitable clinical setting. This article describes potential clinical applications for liver fat quantification of imaging methods for fat detection and quantification, with an emphasis on the advantages and limitations of ultrasonography, computed tomography, and magnetic resonance imaging for quantifying liver fat.