Open AccessThe Involvement of FcR Mechanisms in Antibody-Mediated Rejection
Author(s) -
Chih-Yuan Lee,
Sahar Lotfi-Emran,
Melek M. Erdinc,
Kazunori Murata,
Ergun Velidedeoğlu,
Karen Fox-Talbot,
Jinhuan Wang,
Justin Garyu,
William M. Baldwin,
Barbara Wąsowska
Publication year - 2007
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/01.tp.0000287457.54761.53
Subject(s) - monoclonal antibody , peripheral blood mononuclear cell , major histocompatibility complex , microbiology and biotechnology , cytokine , antibody , immunology , antigen , in vitro , chemistry , in vivo , biology , biochemistry
Antibody-mediated rejection is characterized by macrophage margination against vascular endothelium. The potential interactions triggered by antibodies between endothelial cells (EC) and macrophages have not been examined thoroughly in transplants. We used in vivo and in vitro models of antibody-mediated rejection.