
Tubular Engraftment and Myofibroblast Differentiation of Recipient-Derived Cells After Experimental Kidney Transplantation
Author(s) -
Martine Broekema,
Martin C. Harmsen,
Jasper Koerts,
Theo G. van Kooten,
Gerjan Navis,
Marja J. A. van Luyn,
Eliane R. Popa
Publication year - 2007
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/01.tp.0000285298.05242.f1
Subject(s) - myofibroblast , transplantation , renal stem cell , kidney , population , pathology , kidney transplantation , fibrosis , medicine , regeneration (biology) , stem cell , biology , microbiology and biotechnology , progenitor cell , environmental health
In human renal allografts, recipient-derived cells engrafted in various kidney substructures, have been detected in the long term after transplantation. Here we investigated tubular engraftment and myofibroblast differentiation of recipient-derived cells at short term after experimental kidney transplantation, during a previously described window of regeneration and possible onset of renal interstitial fibrosis.