Open AccessElevated Interleukin-4 Expression in Severe Recurrent Hepatitis C Virus After Liver Transplantation
Author(s) -
Sébastien Dharancy,
Philippe Podevin,
Lynda Aoudjehane,
Frédéric Batteux,
Arielle R. Rosenberg,
Olivier Soubrane,
Yvon Calmus,
Filoména Conti
Publication year - 2007
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/01.tp.0000258729.68871.be
Subject(s) - liver transplantation , medicine , hepatitis c virus , liver biopsy , gastroenterology , transplantation , hepatitis c , immunohistochemistry , interleukin , biopsy , pathology , virus , immunology , cytokine
Chronic hepatitis C virus (HCV) is usually associated with high levels of hepatic interleukin (IL)-2 and low levels of IL-4 transcripts. HCV frequently recurs after liver transplantation, and its course is accelerated in this setting. We compared in situ expression of IL-2 and IL-4 in transplanted and nontransplanted patients with HCV.