Open AccessLong-Term Cell Monitoring of Kidney Recipients After an Antilymphocyte Globulin Induction With and Without Steroids
Author(s) -
Stéphanie Louis,
Marie Audrain,
Diego Cantarovich,
Barbara Schaffrath,
Kay Hofmann,
Uwe Janßen,
Caroline Ballet,
Sophie Brouard,
JeanPaul Soulillou
Publication year - 2007
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/01.tp.0000255683.66156.d3
Subject(s) - immunology , biology , polyclonal antibodies , myeloid , t cell , phenotype , kidney , medicine , endocrinology , immune system , antibody , gene , biochemistry
Because of several side effects, the corticosteroid usage has been minimized in kidney transplantation. The increased acute rejection episodes associated with their withdrawal may counterbalance with induction treatment using polyclonal antilymphocyte globulin (ALG). The effects of ALG on blood cell phenotype have already been the subject of several reports. However, to date, no data are available concerning the comparison of blood phenotype when ALG is given with or without steroids and no gene profiling study has been performed.