Open AccessSubclinical Inflammation and Prothrombotic State in Heart Transplant Recipients: Impact of Cyclosporin Microemulsion vs. Tacrolimus
Author(s) -
Michel White,
Heather J. Ross,
Haissam Haddad,
Marie-Hélène Leblanc,
Normand Racine,
Peter W. Pflugfelder,
Nadia Giannetti,
Ross A. Davies,
Eduardo Ribeiro de Azevêdo,
Debra Isaac,
Jeffrey R. Burton,
Roger K. Ferguson,
Jacques Genest
Publication year - 2006
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/01.tp.0000232286.22319.e0
Subject(s) - medicine , tacrolimus , transplantation , gastroenterology , homocysteine , uric acid
Subclinical inflammation is related to adverse events in patients with coronary artery disease. In the present study, we determined the changes in hemostatic parameters and inflammatory markers in a large cohort of dyslipidemic cardiac transplant recipients compared with dyslipidemic healthy controls, and the effect of cyclosporin microemulsion (CsA) vs. tacrolimus immunoprophylaxis on these parameters.