Open AccessSteroid Withdrawal for Pancreas after Kidney Transplantation in Recipients on Maintenance Prednisone Immunosuppression
Author(s) -
Jonathan A. Fridell,
Avinash Kumar Ágarwal,
John A. Powelson,
William C. Goggins,
Martin L. Milgrom,
Mark D. Pescovitz,
A. Joseph Tector
Publication year - 2006
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/01.tp.0000228904.01482.88
Subject(s) - immunosuppression , medicine , prednisone , tacrolimus , transplantation , pancreas transplantation , maintenance therapy , sirolimus , kidney transplantation , calcineurin , surgery , kidney , gastroenterology , urology , chemotherapy
Steroid withdrawal from patients taking prednisone for their renal allograft at the time of reinduction of immunosuppression for subsequent pancreas after kidney (PAK) transplantation has not been explored. Our expectation was that lymphocyte depletion, in conjunction with an augmentation of immunosuppression at the time of pancreas transplantation would protect the recipient from rejection of the renal allograft when chronic maintenance steroids are withdrawn.