Open AccessPlasma Cell-Rich Rejection Processes in Renal Transplantation: Morphology and Prognostic Relevance
Author(s) -
Valeria Gärtner,
Thomas Eigentler,
Richard Viebahn
Publication year - 2006
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/01.tp.0000215014.40595.ab
Subject(s) - transplantation , medicine , renal function , kidney transplantation , stage (stratigraphy) , renal transplant , pathology , urology , gastroenterology , immunology , biology , paleontology
Renal transplantation is the most effective therapy in end-stage renal disease. The prognosis of transplant survival is still determined by rejection. Morphologically, this involves interstitial rejection with potential development of vascular rejection (VR) and/or glomerular rejection processes, designated as transplant glomerulopathy (TGP). The cellular infiltrates are usually dominated by lymphocytes and macrophages in differing quantity, characterizing the severity of the rejection processes.