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Influence of Age in Renal Transplant Infections: Cases and Controls Study
Author(s) -
Isabel Trouillhet,
Natividad Benito,
Carlos Cervera,
Paula Rivas,
Frederic Cofan,
Manuel Almela,
María Ángeles Marcos,
Jorge Puig de la Bellacasa,
Tomàs Pumarola,
Federico Oppenheimer,
Asunción MorenoCamacho
Publication year - 2005
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/01.tp.0000173822.05877.d7
Subject(s) - medicine , incidence (geometry) , odds ratio , urinary system , kidney transplantation , transplantation , kidney , kidney transplant , case control study , gastroenterology , surgery , physics , optics
Kidney transplantation in elderly patients is a good therapeutic option, but the incidence of infections compared to younger patients must be studied. Case and control study was performed with 40 cases (patients older than 65) and 40 controls (younger than 65) receiving a kidney transplant between January 2000 and August 2002. In 32 cases (80%) and in 14 controls (32%), some type of infection appeared during the follow-up (odds ratio [OR] 5; 95% CI 1.6-20). The percentage of patients with bacterial infections was higher in the cases (70% vs. 28%; OR 5.7; 95% CI 1.9-20), especially for urinary infections. No differences for viral and fungal infections were observed in the two groups. Mortality rate was 13% in the cases (5% due to infections), whereas there was no controls' mortality. Although the number of bacterial infections was higher, kidney transplantation in elderly patients is a secure procedure.

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