Influence of Pancreas Preservation on Human Islet Isolation Outcomes: Impact of the Two-Layer Method
Author(s) -
Toshiaki Tsujimura,
Yoshikazu Kuroda,
José G. Ávila,
Tatsuya Kin,
José Oberholzer,
A. M. James Shapiro,
Jonathan R. T. Lakey
Publication year - 2004
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/01.tp.0000133515.37892.d5
Subject(s) - islet , viaspan , transplantation , pancreas , cold storage , medicine , cadaveric spasm , isolation (microbiology) , andrology , urology , biology , diabetes mellitus , surgery , endocrinology , bioinformatics , horticulture
Human pancreas preservation for islet transplantation holds additional challenges and considerations compared with whole pancreas transplantation. The purpose of this study was to clarify the limitations of the University of Wisconsin (UW) solution and the potentials of the two-layer method (TLM) for pancreas preservation before human islet isolation.
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