Open AccessLIVER TRANSPLANTATION-INDUCED ANTIHISTONE H1 AUTOANTIBODIES SUPPRESS MIXED LYMPHOCYTE REACTION
Author(s) -
Toshiaki Nakano,
Seiji Kawamoto,
Chia-Yun Lai,
Tetsuya Sasaki,
Tsunehiro Aki,
Seiko Shigeta,
Takeshi Goto,
Shuji Sato,
Shigeru Goto,
ChaoLong Chen,
Kazuhisa Ono
Publication year - 2004
Publication title -
transplantation
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/01.tp.0000123079.10650.71
Subject(s) - immunology , autoantibody , polyclonal antibodies , antibody , mixed lymphocyte reaction , liver transplantation , antigen , transplantation , histone , lymphocyte , medicine , biology , immune system , t cell , biochemistry , gene
In a rat model of orthotopic liver transplantation (OLT), recipient serum after OLT (post-OLT serum) has been reported to prevent allograft rejection. However, the molecular identities of immunosuppressive factors, which are in the early stage of post-OLT, remain elusive. This study was aimed to identify immunodominant suppressive factors present in early post-OLT serum.