Open AccessINTRAVENOUS IMMUNOGLOBULIN: A SAFE OPTION FOR TREATMENT OF STEROID-RESISTANT REJECTION IN THE PRESENCE OF INFECTION
Author(s) -
Venkatesh Moger,
Machiraju S. Ravishankar,
Vinay Sakhuja,
Harbir Singh Kohli,
Kamal Sud,
Krishan Lal Gupta,
Vivekanand Jha
Publication year - 2004
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/01.tp.0000122415.08639.53
Subject(s) - medicine , antibody , concomitant , immunology , steroid , immunoglobulin g , hormone
Management of recurrent allograft rejection is a risky proposition, especially in the presence of infections. Both steroids and antibody therapy worsen the infection risk. We successfully treated steroid-resistant rejection with intravenous immunoglobulin (IVIG) in two patients who had concomitant infections. IVIG should be considered the treatment of choice for management of steroid-resistant rejection in the presence of serious infection.