RAPID ESTABLISHMENT OF LONG-TERM CULTURE-INITIATING CELLS OF DONOR ORIGIN AFTER NONMYELOABLATIVE ALLOGENEIC HEMATOPOIETIC STEM-CELL TRANSPLANTATION, AND SIGNIFICANT PROGNOSTIC IMPACT OF DONOR T-CELL CHIMERISM ON STABLE ENGRAFTMENT AND PROGRESSION-FREE SURVIVAL | Zendy

Felix Keil | Zendy; Erika Prinz | Zendy; Karin S. Moser | Zendy; Christine Mannhalter | Zendy; Peter Kalhs | Zendy; Nina Worel | Zendy; Werner Rabitsch | Zendy; Axel Schulenburg | Zendy; Margit Mitterbauer | Zendy; Hildegard Greinix | Zendy

Open Access

RAPID ESTABLISHMENT OF LONG-TERM CULTURE-INITIATING CELLS OF DONOR ORIGIN AFTER NONMYELOABLATIVE ALLOGENEIC HEMATOPOIETIC STEM-CELL TRANSPLANTATION, AND SIGNIFICANT PROGNOSTIC IMPACT OF DONOR T-CELL CHIMERISM ON STABLE ENGRAFTMENT AND PROGRESSION-FREE SURVIVAL

Author(s) -

Felix Keil,

Erika Prinz,

Karin S. Moser,

Christine Mannhalter,

Peter Kalhs,

Nina Worel,

Werner Rabitsch,

Axel Schulenburg,

Margit Mitterbauer,

Hildegard Greinix

Publication year - 2003

Publication title -

transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.45

H-Index - 204

eISSN - 1534-6080

pISSN - 0041-1337

DOI - 10.1097/01.tp.0000071862.42835.76

Subject(s) - stem cell , fludarabine , haematopoiesis , medicine , myeloid , cd34 , transplantation , immunology , transplantation chimera , hematopoietic stem cell transplantation , progenitor cell , total body irradiation , cancer research , biology , chemotherapy , cyclophosphamide , hematopoietic cell , genetics

Nonmyeloablative allogeneic hematopoietic stem-cell transplantation (NST) allows establishment of donor hematopoiesis without eradication of recipient stem cells by chemoradiotherapy. Quantification of donor chimerism may predict graft failure and relapse.

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