Open AccessComparative study of allograft survival of heterotopic and orthotopic small bowel transplantation in rat1
Author(s) -
Wei Guo,
Lei Tian,
Margaret J. Dallmann,
Paul K. H. Tam
Publication year - 2003
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/01.tp.0000065294.04793.11
Subject(s) - medicine , immunosuppression , transplantation , small intestine , surgery , gastroenterology , urology
Small bowel allografts can either be placed heterotopically or orthotopically. In heterotopic small bowel transplantation (H-SBT), the host small intestine containing a substantial amount of gut-associated lymphoid tissue is removed, whereas in conventional orthotopic small bowel transplantation (O-SBT) it is retained. This study compared the allograft survival of H-SBT and O-SBT and evaluated the effect of retaining the host intestine in O-SBT in an altered O-SBT (AO-SBT) model.