Open AccessEndothelial cell chimerism does not influence allograft tolerance in liver transplant patients after withdrawal of immunosuppression1
Author(s) -
J.A. Pons,
José Yelamos,
Pablo Ramı́rez,
María Oliver-Bonet,
Alicia Sánchez,
Manolo Rodríguez-Gago,
J. Navarro,
Juan Bermejo,
R Robles,
Pascual Parrilla
Publication year - 2003
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/01.tp.0000058472.71775.7d
Subject(s) - immunosuppression , medicine , liver transplantation , endothelial stem cell , immunology , immune tolerance , gastroenterology , transplantation , biology , antigen , biochemistry , in vitro
Human liver allografts sometimes show self-induced permanent tolerance without immunosuppression. It has recently been proposed that the replacement of liver donor endothelial cells by recipient cells could confer a survival advantage. The aim of this study was to analyze liver endothelial cell replacement in relation to the response (tolerance or rejection) after withdrawal of immunosuppression in liver transplant patients.