Open AccessSubthreshold doses of nebulized prostacyclin and rolipram synergistaically protect against lung ischemia-reperfusion.
Author(s) -
Hartwig Schütte,
Alexander Schell,
Christoph Schäfer,
Hossein Ardeschir Ghofrani,
Ralph T. Schermuly,
Werner Seeger,
Friedrich Grimminger
Publication year - 2003
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/01.tp.0000053751.22207.4e
Subject(s) - rolipram , medicine , ischemia , prostacyclin , lung , pulmonary edema , pharmacology , anesthesia , vascular permeability , edema , chemistry , phosphodiesterase , biochemistry , enzyme
Pulmonary edema caused by increased microvascular permeability is an important feature of lung ischemia-reperfusion (I/R) injury.