Open AccessAFP mRNA Detected in Bone Marrow by Real-Time Quantitative RT-PCR Analysis Predicts Survival and Recurrence After Curative Hepatectomy for Hepatocellular Carcinoma
Author(s) -
Toshiya Kamiyama,
Masato Takahashi,
Takahito Nakagawa,
Koji Nakanishi,
Hirofumi Kamachi,
Tomomi Suzuki,
Tsuyoshi Shimamura,
Masahiko Taniguchi,
Michitaka Ozaki,
Michiaki Matsushita,
Hiroyuki Furukawa,
Satoru Todo
Publication year - 2006
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/01.sla.0000234840.74526.2b
Subject(s) - medicine , hepatocellular carcinoma , hepatectomy , bone marrow , gastroenterology , real time polymerase chain reaction , messenger rna , pathology , liver cancer , surgery , resection , gene , biochemistry , chemistry
To determine whether detection of hepatocellular carcinoma (HCC) cells by real-time quantitative RT-PCR targeting of alpha-fetoprotein mRNA (AFP mRNA) before or after curative hepatectomy predicts HCC recurrence and patient survival.