Open AccessTumor Necrosis Factor-alpha Damages Tumor Blood Vessel Integrity by Targeting VE-Cadherin
Author(s) -
Chandrakala Me,
Antoinette Ghartey,
Robert J. Canter,
Michael D. Feldman,
Douglas L. Fraker
Publication year - 2006
Publication title -
annals of surgery
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/01.sla.0000231723.81218.72
Subject(s) - medicine , tumor necrosis factor alpha , melphalan , necrosis , pathology , endothelial stem cell , limb perfusion , endothelium , cancer research , perfusion , immunology , biology , chemotherapy , in vitro , biochemistry
Isolated limb perfusion using high-dose human tumor necrosis factor-alpha with melphalan is effective therapy for bulky extremity in-transit melanoma and sarcoma.