Open AccessMacrophage Migration Inhibitory Factor Stimulates Angiogenic Factor Expression and Correlates With Differentiation and Lymph Node Status in Patients With Esophageal Squamous Cell Carcinoma
Author(s) -
Yi Ren,
Simon Law,
Xin Huang,
Ping Yin Lee,
Michael Bacher,
Gopesh Srivastava,
John Wong
Publication year - 2005
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/01.sla.0000168555.97710.bb
Subject(s) - medicine , macrophage migration inhibitory factor , esophageal squamous cell carcinoma , lymph node , cancer research , macrophage , basal cell , oncology , pathology , carcinoma , cytokine , in vitro , biochemistry , chemistry
The objectives of this study were: 1) to examine the expression of macrophage migration inhibitory factor (MIF) in esophageal squamous cell carcinoma (ESCC); 2) to see if a relationship exists between MIF expression, clinicopathologic features, and long-term prognosis; and 3) to ascertain the possible biologic function of MIF in angiogenesis.