Open AccessAssociation of Angiotensin-Converting Enzyme Insertion/Deletion Polymorphism With Serum Level and Development of Pulmonary Complications Following Esophagectomy
Author(s) -
Jang-Ming Lee,
AnChi Lo,
Shi-Yi Yang,
Huei-Shian Tsau,
Robert J. Chen,
Yung-Chie Lee
Publication year - 2005
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/01.sla.0000157132.08833.98
Subject(s) - medicine , odds ratio , esophagectomy , genotype , gastroenterology , angiotensin converting enzyme , confidence interval , esophageal cancer , allele , hypoalbuminemia , surgery , cancer , genetics , blood pressure , gene , biology
Pulmonary complications remain the major cause of postoperative mortality in patients with esophageal cancer undergoing esophagectomy. It was unclear whether this dismal complication has a genetic predisposition. We therefore investigated the role of an angiotensin-converting enzyme (ACE) insertion/deletion polymorphism in developing these complications.