Open AccessTreatment With Simvastatin Suppresses the Development of Experimental Abdominal Aortic Aneurysms in Normal and Hypercholesterolemic Mice
Author(s) -
Éric Steinmetz,
Celine Buckley,
Murray L. Shames,
Terri L. Ennis,
Sarah J. Vanvickle-Chavez,
Dongli Mao,
Lee A. Goeddel,
Cherady J. Hawkins,
Robert W. Thompson
Publication year - 2005
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/01.sla.0000150258.36236.e0
Subject(s) - simvastatin , medicine , elastase , elastin , aorta , abdominal aorta , endocrinology , pancreatic elastase , cholesterol , pathology , biochemistry , chemistry , enzyme
To determine if treatment with hydroxymethylglutaryl-coenzyme A reductase inhibitors (statins) can influence the development of experimental abdominal aortic aneurysms (AAAs).