Open AccessPancreatic Duct Ligation Reduces Lung Injury Following Trauma and Hemorrhagic Shock
Author(s) -
David B. Cohen,
Louis J. Magnotti,
Quan Lu,
Dakang Xu,
Tamara L. Berezina,
Sergey B. Zaets,
Carlos Álvarez,
George W. Machiedo,
Edwin A. Deitch
Publication year - 2004
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/01.sla.0000143809.44221.9b
Subject(s) - medicine , lung , bronchoalveolar lavage , pancreas , pancreatic duct , proteases , ligation , pancreatic injury , pathology , gastroenterology , biology , biochemistry , enzyme
To determine whether pancreatic digestive enzymes released into the ischemic gut during an episode of T/HS are involved in the generation of distant organ injury. This hypothesis was tested by examining the effect of PDL on T/HS-induced intestinal injury, lung injury, and RBC deformability.