Open AccessGhrelin
Author(s) -
James T. Wu,
John G. Kral
Publication year - 2004
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/01.sla.0000118561.54919.61
Subject(s) - ghrelin , orexigenic , endocrinology , medicine , growth hormone secretagogue receptor , energy homeostasis , hormone , appetite , anabolism , leptin , receptor , neuropeptide , neuropeptide y receptor , obesity
Ghrelin is a novel gastric hormone recognized in 1999 as a mediator of growth hormone release. Since growth hormone is anabolic, an important function of ghrelin may be to coordinate energy needs with the growth process. Newly discovered biologic roles of ghrelin imply that it may have other important physiological functions as well. This is a review of recent clinically relevant, yet less well-known, physiologic actions of ghrelin.