Open AccessEvolution of HIV Resistance Mutations in Patients Maintained on a Stable Treatment Regimen After Virologic Failure
Author(s) -
Matthew Bidwell Goetz,
Monique Ferguson,
Xueliang Han,
G. Steven McMillan,
Marty St. Clair,
Keith A. Pappa,
Daniel McCler,
William A. O’Brien
Publication year - 2006
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/01.qai.0000245882.28391.0c
Subject(s) - protease inhibitor (pharmacology) , lamivudine , regimen , ritonavir , protease , thymidine , biology , virology , viral load , medicine , indinavir , hiv 1 protease , pharmacology , immunology , gastroenterology , virus , genetics , dna , enzyme , antiretroviral therapy , biochemistry , hepatitis b virus
We compared the rate of emergence of thymidine analogue mutations (TAMs) and major protease inhibitor mutations in adherent patients who remained on stable treatment with a thymidine analogue and/or protease inhibitor after the onset of virologic failure.