Dopamine is not an independent risk factor for reduced amikacin clearance in extremely low-birth-weight infants
Author(s) -
Karel Allegaert,
Anne Debeer,
Veerle Cossey,
Maissa Rayyan,
Hugo Devlieger
Publication year - 2006
Publication title -
pediatric critical care medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.299
H-Index - 87
eISSN - 1947-3893
pISSN - 1529-7535
DOI - 10.1097/01.pcc.0000200971.65255.f0
Subject(s) - medicine , amikacin , dopamine , risk factor , low birth weight , birth weight , pediatrics , pregnancy , antibiotics , genetics , microbiology and biotechnology , biology
Important inter-individual variability in amikacin clearance was observed in preterm infants, only in part explained by gestational age (GA), birth weight, or coadministration of nonselective cyclo-oxygenase (COX) inhibitor. We therefore evaluated whether dopamine had an additional effect on amikacin clearance.
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