Open AccessEosinophilic asthma and the role of monoclonal antibodies
Author(s) -
Lynda Jarrell
Publication year - 2021
Publication title -
the nurse practitioner/the nurse practitioner
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.15
H-Index - 21
eISSN - 1538-8662
pISSN - 0361-1817
DOI - 10.1097/01.npr.0000737188.21326.c1
Subject(s) - monoclonal antibody , exhaled nitric oxide , medicine , asthma , sputum , eosinophilic , immunology , monoclonal , antibody , pathology , spirometry , tuberculosis
Eosinophilic asthma presents with continuous airway inflammation resistant to inhaled corticosteroids but responsive to oral glucocorticoids and monoclonal antibodies. Diagnostic criteria include significantly elevated blood or sputum eosinophils and/or fractional exhaled nitric oxide. Five monoclonal antibodies are used for treatment, with accurate diagnosis and early intervention essential to better outcomes.