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Quality of Life and Head and Neck Cancer: A 5 Year Prospective Study
Author(s) -
Abendstein Helmut,
Nordgren Mats,
Boysen Morten,
Jannert Magnus,
Silander Ewa,
AhlnerElmqvist Marianne,
Hammerlid Eva,
Bjordal Kristin
Publication year - 2005
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1097/01.mlg.0000181507.69620.14
Subject(s) - medicine , quality of life (healthcare) , head and neck cancer , prospective cohort study , cancer , head and neck , physical therapy , surgery , nursing
Objectives: Assessment of health‐related quality of life (HRQL) in head and neck cancer patients from diagnosis to 5 years after start of treatment. Study Design: A prospective, descriptive study Methods: three hundred fifty‐seven patients from Norway and Sweden filled in HRQL questionnaires, the European Organisation for Research and Treatment of Cancer (EORTC) QLQ–C30 and the EORTC QLQ‐H&N35, six times during the first year and then after 5 years. At 5 years, 167 (87%) of the 192 living patients filled in questionnaires. Results: Group data: clinical significant improvements in HRQL were not found between 1 and 5 years. Problems with teeth, opening of the mouth, dryness in the mouth, and sticky saliva were persistent or worsening. Similar findings were found regardless of sex, age, stage, or site when clinical significant changes are considered. Patients who died between 1 and 5 years reported reduced HRQL on 15 of 28 scales at 1 year compared with the survivors. Individual data: 40% of patients reported improved global HRQL from diagnosis to 5 years after start of treatment. In addition, 11% had “top scores” at both assessment points. The pattern in global HRQL scores also applies for most of the other function and symptom scales. Conclusion: After the first year after treatment, recovery of the persisting side effects of treatment cannot be expected for the group as a whole. Patients must be prepared for this. Some individual patients experience improvement in global HRQL. HRQL assessments in daily clinical practice can identify patients who are in need of additional support and symptom relief.