Open AccessInfectious disease considerations in immunocompromised patients
Author(s) -
Bridget McGrath,
Mary Broadhurst,
Christopher Roman
Publication year - 2020
Publication title -
journal of the american academy of physician assistants
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.24
H-Index - 17
ISSN - 0893-7400
DOI - 10.1097/01.jaa.0000694948.01963.f4
Subject(s) - immunosuppression , medicine , intensive care medicine , asplenia , disease , infectious disease (medical specialty) , population , immunology , spleen , environmental health
Immunocompromised patients account for about 3% of the US population. Complications arising from infection are common in these patients and can present diagnostic and therapeutic challenges. This article describes the pathophysiology of immunosuppression in five common immunocompromised states-asplenia, HIV infection, solid organ transplant, biologic use, and cancer-as well as specific infectious risks and considerations for affected patients and how to manage them.