Open AccessTREATMENT OF DIENTAMOEBA FRAGILIS INFECTION WITH PAROMOMYCIN
Author(s) -
Olivier Vandenberg,
Hichem Souayah,
Françoise Mouchet,
Anne Dediste,
Tom van Gool
Publication year - 2007
Publication title -
the pediatric infectious disease journal/the pediatric infectious disease journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 140
eISSN - 1532-0987
pISSN - 0891-3668
DOI - 10.1097/01.inf.0000247139.89191.91
Subject(s) - paromomycin , medicine , antibiotics , pharmacotherapy , microbiology and biotechnology , aminoglycoside , biology
Treatment with paromomycin (25-35 mg/kg/d for 7 days) was evaluated prospectively in 15 children with Dientamoeba fragilis infection after 1-month follow-up. At the end of the study, parasitologic effectiveness and clinical improvement were observed in 12/15 (80%) and 13/15 (87%) patients, respectively. Paromomycin appears to be an effective drug for treatment of D. fragilis infection in children.