Open AccessANTIBODIES TO BORNA DISEASE VIRUS IN SUBACUTE SCLEROSING PANENCEPHALITIS
Author(s) -
Serdal Güngör,
Banu Anlar,
Nuri Turan,
Hüseyin Yılmaz,
Christopher R Helps,
D. A. Harbour
Publication year - 2005
Publication title -
the pediatric infectious disease journal/the pediatric infectious disease journal
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 140
eISSN - 1532-0987
pISSN - 0891-3668
DOI - 10.1097/01.inf.0000178307.70429.75
Subject(s) - subacute sclerosing panencephalitis , measles virus , virology , measles , antibody , medicine , virus , disease , immunology , pathology , vaccination
Mechanisms causing persistence and reactivation of measles virus in subacute sclerosing panencephalitis (SSPE) are unknown. Borna disease virus (BDV) frequently causes latent or persistent infection in the nervous system. We investigated a possible association of these viruses in SSPE. Although BDV seropositivity was similar in SSPE and control groups, SSPE patients with high antibodies to BDV had earlier and more rapid disease. The findings suggest that BDV might be involved in the course, but not in the etiopathogenesis, of SSPE.