Open AccessClinical, Virologic and Immunologic Profiles of a Young Infant With Severe Acute Respiratory Syndrome
Author(s) -
Frankie Wai Tsoi Cheng,
Enders K. O. Ng,
Albert Martin Li,
Ellis K.L. Hon,
Rossa W.K. Chiu,
Y.M. Dennis Lo,
Pak Cheung Ng
Publication year - 2005
Publication title -
the pediatric infectious disease journal/the pediatric infectious disease journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 140
eISSN - 1532-0987
pISSN - 0891-3668
DOI - 10.1097/01.inf.0000164703.61282.3b
Subject(s) - viremia , respiratory system , ribavirin , immunology , medicine , chemokine , reverse transcription polymerase chain reaction , viral load , viral replication , virology , reverse transcriptase , polymerase chain reaction , coronavirus , virus , disease , covid-19 , biology , inflammation , infectious disease (medical specialty) , gene , gene expression , hepatitis c virus , biochemistry
The clinical findings, plasma viral load, cytokines and chemokines of a 4-month-old infant with severe acute respiratory syndrome (SARS) were assessed at different phases of the disease. Ribavirin failed to inhibit SARS coronavirus (SARS-CoV) replication. One-step real time reverse transcription-polymerase chain reaction for plasma SARS-CoV RNA quantification was useful for early diagnosis and monitoring viremia.