Open AccessSuccessful cidofovir treatment of adenovirus-associated hemorrhagic cystitis and renal dysfunction after allogeneic bone marrow transplantation
Author(s) -
Naoki Hatakeyama,
Nobuhiro Suzuki,
Tooru Kudoh,
Tsukasa Hori,
Nobuo Mizue,
Hiroyuki Tsutsumi
Publication year - 2003
Publication title -
the pediatric infectious disease journal/the pediatric infectious disease journal
Language(s) - English
Resource type - Journals
eISSN - 1532-0987
pISSN - 0891-3668
DOI - 10.1097/01.inf.0000091399.29505.21
Subject(s) - cidofovir , hemorrhagic cystitis , medicine , vidarabine , bk virus , transplantation , urinary system , bone marrow transplantation , bone marrow , urology , kidney transplantation , immunology , chemotherapy , virus , hematopoietic stem cell transplantation , cyclophosphamide , fludarabine
We present a patient who developed hemorrhagic cystitis and renal dysfunction after unrelated bone marrow transplantation. Polyoma BK virus and adenovirus 11 were detected in the urine. Vidarabine was administered without effect. Relatively low dose cidofovir was efficacious. Renal function improved, and the urinary secretion of adenovirus stopped.