Open AccessHeterotopic Bone Formation Around Sintered Porous-Surfaced Ti-6Al-4V Implants Coated with Native Bone Morphogenetic Proteins
Author(s) -
Ziv Simon,
Douglas Deporter,
Robert M. Pilliar,
Cameron M. L. Clokie
Publication year - 2006
Publication title -
implant dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.538
H-Index - 65
eISSN - 1538-2982
pISSN - 1056-6163
DOI - 10.1097/01.id.0000226754.71828.6b
Subject(s) - osseointegration , implant , materials science , gelatin , pouch , biomedical engineering , porosity , bone growth , dentistry , composite material , chemistry , anatomy , medicine , surgery , biochemistry
Coating endosseous dental implants with growth factors such as bone morphogenetic proteins (BMPs) may be one way to accelerate and/or enhance the quality of osseointegration. The purpose of this study was to investigate in the murine muscle pouch model whether sintered porous-surfaced titanium alloy implants coated with BMPs would lead to heterotopic bone formation around and within the implant surface geometry.