Open AccessBone Formation Around Titanium Implants in the Rat Tibia: Role of Insulin
Author(s) -
José Tadeu Tesseroli de Siqueira,
Simone C. Cavalher-Machado,
Victor E. AranaChavez,
Paulina Sannomiya
Publication year - 2003
Publication title -
implant dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.538
H-Index - 65
eISSN - 1538-2982
pISSN - 1056-6163
DOI - 10.1097/01.id.0000074440.04609.4f
Subject(s) - osseointegration , implant , alloxan , insulin , diabetes mellitus , medicine , tibia , dentistry , bone remodeling , bone healing , endocrinology , surgery
Clinical and experimental studies show, with few exceptions, that type 1 diabetes mellitus is associated with a delay in bone repair around endosseous implants. The effect of insulin in bone repair/remodeling is not completely understood. The aim of this study was to investigate the course of histological and ultrastructural changes of the osseointegration process under the influence of insulin.