Open AccessP1492: PHARMACODYNAMIC EFFECTS OF AG‐946, A HIGHLY POTENT NOVEL ACTIVATOR OF PYRUVATE KINASE, IN EX VIVO TREATMENT OF RED BLOOD CELLS FROM SICKLE CELL DISEASE PATIENTS
Author(s) -
Rab M.,
Dijk M.,
Bos J.,
Oirschot B.,
Gerrits J.,
Kosinski P.,
Kung C.,
Jans J.,
Beers E.,
Dang L.,
Wijk R.
Publication year - 2022
Publication title -
hemasphere
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 11
ISSN - 2572-9241
DOI - 10.1097/01.hs9.0000848824.02079.e8
Subject(s) - ex vivo , pyruvate kinase , glycolysis , in vivo , medicine , pyruvate kinase deficiency , hemoglobin , endocrinology , pharmacology , chemistry , biochemistry , biology , metabolism , in vitro , microbiology and biotechnology