Open AccessMaternal Obesity, Gestational Diabetes, and Central Nervous System Birth Defects
Author(s) -
Joanna Anderson,
D. Kim Waller,
Mark A. Canfield,
Gary M. Shaw,
Margaret Watkins,
Martha M. Werler
Publication year - 2005
Publication title -
epidemiology
Language(s) - English
Resource type - Journals
eISSN - 1531-5487
pISSN - 1044-3983
DOI - 10.1097/01.ede.0000147122.97061.bb
Subject(s) - medicine , spina bifida , anencephaly , gestational diabetes , odds ratio , holoprosencephaly , body mass index , obstetrics , obesity , population , offspring , diabetes mellitus , pediatrics , pregnancy , gestation , endocrinology , fetus , biology , environmental health , genetics
Maternal obesity and diabetes are both associated with increased risk of congenital central nervous system (CNS) malformations in the offspring and may share a common underlying mechanism. Our objective was to evaluate whether gestational diabetes influenced the association of prepregnancy maternal obesity and risks for CNS birth defects.