Open AccessDoes Pregnancy Induce the Shedding of Premalignant Ovarian Cells?
Author(s) -
Klaus Rostgaard,
Jan Wohlfahrt,
Per Kragh Andersen,
Henrik Hjalgrim,
Mørten Frisch,
Tine Westergaard,
Mads Melbye
Publication year - 2003
Publication title -
epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.901
H-Index - 173
eISSN - 1531-5487
pISSN - 1044-3983
DOI - 10.1097/01.ede.0000050701.99792.95
Subject(s) - pregnancy , ovarian cancer , medicine , cohort , obstetrics , ovary , physiology , cohort study , gynecology , oncology , cancer , biology , genetics
High parity is associated with reduced risk of ovarian cancer. One hypothesis is that pregnancy is associated with clearance of a fraction of the genetically modified (premalignant) cells from the ovaries.