Open AccessDoes Change in ESR and CRP Guide the Timing of Two-stage Arthroplasty Reimplantation?
Author(s) -
Jeffrey B. Stambough,
Brian Curtin,
Susan M. Odum,
Michael B. Cross,
J. Ryan Martin,
Thomas K. Fehring
Publication year - 2018
Publication title -
clinical orthopaedics and related research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.178
H-Index - 204
eISSN - 1528-1132
pISSN - 0009-921X
DOI - 10.1097/01.blo.0000533618.31937.45
Subject(s) - medicine , arthroplasty , orthopedic surgery , replantation , stage (stratigraphy) , sports medicine , surgery , arthroplasty replacement , physical therapy , paleontology , biology
Two-stage reimplantation arthroplasty is a commonly used approach for treating chronic periprosthetic joint infections. A prereimplantation threshold value of erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) to determine infection eradication and the proper timing of reimplantation remains ill defined. We theorized that rather than a specific numeric threshold, a percentage of improvement in these serology markers might improve diagnostic accuracy in determining the timing of reimplantation.