Open AccessCGH of microdissected Kaposi's sarcoma lesions reveals recurrent loss of chromosome Y in early and additional chromosomal changes in late tumour stages
Author(s) -
Pawan Pyakurel,
Ulrike Montag,
Esmeralda CastañosVélez,
Ephata Kaaya,
Birger Christensson,
Holger Tönnies,
Peter Biberfeld,
Thomas Heiden
Publication year - 2006
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/01.aids.0000244199.72887.3d
Subject(s) - biology , microdissection , comparative genomic hybridization , fluorescence in situ hybridization , sarcoma , chromosome instability , cytogenetics , chromosome , aneuploidy , karyotype , pathology , microbiology and biotechnology , genetics , medicine , gene
It is still unclear if Kaposi's sarcoma (KS) is a monoclonal cell proliferation or a polyclonal, hyperplastic, reactive process. Reports on KS cytogenetics are few and restricted to late stage disease and cell lines.