
Homozygous and Heterozygous CCR5-Δ32 Genotypes Are Associated With Resistance to HIV Infection
Author(s) -
Michael Marmor,
Haynes W. Sheppard,
Deborah Donnell,
Sam Bozeman,
Connie Celum,
Susan Buchbinder,
Beryl A. Koblin,
George R. Seage
Publication year - 2001
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/00126334-200108150-00009
Subject(s) - medicine , genotype , serostatus , cohort , men who have sex with men , human immunodeficiency virus (hiv) , demography , immunology , biology , viral load , genetics , syphilis , sociology , gene
To investigate evidence for resistance to HIV-1 infection associated with the heterozygous genotype CCR5-+/Delta32 and with the homozygous genotype CCR5-Delta32/Delta32, which results in a nonfunctional CCR5 receptor.