Open AccessReanalysis of the HIV-1 Circulating Recombinant Form A/E (CRF01_AE): Evidence of A/E/G Recombination
Author(s) -
Gkikas Magiorkinis,
Dimitris Paraskevis,
Emmanouil Magiorkinis,
AnneMieke Vandamme,
Angelos Hatzakis
Publication year - 2002
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/00042560-200205010-00017
Subject(s) - recombination , recombinant dna , biology , human immunodeficiency virus (hiv) , virology , lentivirus , genetics , southeast asia , viral disease , gene , history , ancient history
Circulating recombinant form (CRF) 01_AE caused an extensive HIV-1 epidemic in Thailand and Southeast Asia. Reanalysis of the recombination pattern of CRF01_AE suggested a more complicated pattern of mosaicism consisting of subtypes A, G, and E. These findings provide evidence that CRF01_AE originated from recombination between at least three different subtypes.