Open AccessLow Frequency of Severe Hepatotoxicity and Association With HCV Coinfection in HIV-Positive Patients Treated With HAART
Author(s) -
Antonella d’Arminio Monforte,
Roberto Bugarini,
Patrizio Pezzotti,
Andrea De Luca,
Andrea Antinori,
Cristina Mussini,
G. M. Vigevani,
Umberto Tirelli,
Raffaele Bruno,
F M Gritti,
Marcello Piazza,
Silvia Chigiotti,
Antonio Chirianni,
Carlo de Stefano,
Eligio Pizzigallo,
Oreste Perrella,
Mauro Moroni
Publication year - 2001
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/00042560-200110010-00002
Subject(s) - coinfection , medicine , human immunodeficiency virus (hiv) , immunology , virology
Highly active antiretroviral therapy (HAART) is strongly effective in reducing morbidity and mortality in HIV-1-positive individuals. Its main drawback is the potential toxicity. Data on the frequency and determinants of severe hepatotoxicity in a clinical setting are still sparse.