Open AccessAnisocoria Associated With the Medical Treatment of Irritable Bowel Syndrome
Author(s) -
Jonathan D. Nussdorf,
Eric L. Berman
Publication year - 2000
Publication title -
journal of neuro-ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.586
H-Index - 55
eISSN - 1536-5166
pISSN - 1070-8022
DOI - 10.1097/00041327-200020020-00007
Subject(s) - anisocoria , medicine , irritable bowel syndrome , anticholinergic , anticholinergic agents , anesthesia , resiniferatoxin , scopolamine , mydriasis , gastroenterology , pupil , psychology , receptor , neuroscience , transient receptor potential channel , trpv1
A case of anisocoria associated with oral pharmacologic treatment of irritable bowel syndrome is reported. A 26-year-old woman developed sudden onset of anisocoria and compromised accommodation that lasted 2 days after the use of oral scopolamine methylbromide for treatment of irritable bowel syndrome. The anisocoria and compromised accommodation occurred after contamination of the ocular surface after administration of scopolamine methylbromide and resolved within 1 week without further contamination. Oral preparations used for the pharmacologic treatment of irritable bowel syndrome can cause anisocoria due to anticholinergic pharmacologic blockade of the iris sphincter muscle.