Open AccessGenetic Polymorphisms in ABCB1 Influence the Pharmacodynamic Effects of Tacrolimus on T Cells
Author(s) -
Ramin Vafadari,
Rachida Bouamar,
Dennis A. Hesselink,
Ron H. N. van Schaik,
Rens Kraaijeveld,
Willem Weimar,
Carla C. Baan,
Teun van Gelder
Publication year - 2012
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/00007890-201211271-02232
Subject(s) - rhodamine 123 , efflux , verapamil , p glycoprotein , pharmacology , single nucleotide polymorphism , cd8 , t cell , genotype , chemistry , ex vivo , pharmacodynamics , tacrolimus , pharmacokinetics , biology , medicine , microbiology and biotechnology , immunology , immune system , transplantation , in vitro , biochemistry , multiple drug resistance , gene , calcium , antibiotics