Open AccessHuman islet transplantation from pancreases with prolonged cold ischemia using additional preservation by the two-layer (UW solution/perfluorochemical) cold-storage method
Author(s) -
Takuya Tsujimura,
Yoshikazu Kuroda,
Tatsuya Kin,
José G. Ávila,
Ray V. Rajotte,
Gregory S. Korbutt,
Edmond A. Ryan,
A. M. James Shapiro,
Jonathan R. T. Lakey
Publication year - 2002
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/00007890-200212270-00007
Subject(s) - viaspan , cold storage , islet , transplantation , medicine , machine perfusion , perfusion , surgery , biology , insulin , horticulture , liver transplantation
A two-layer (University of Wisconsin solution/perfluorochemical [UW/PFC]) cold-storage method delivers sufficient oxygen to the pancreas during preservation and restores the ischemically damaged pancreas. In this study, we determined whether the additional preservation by the two-layer method could improve islet recovery from human pancreases with prolonged cold storage in UW.