Open AccessAssociation of the CD134/CD134L costimulatory pathway with acute rejection of small bowel allograft1
Author(s) -
Lei Tian,
Weihong Guo,
Zhengwei Yuan,
Vincent Chi Hang Lui,
John Chan,
Hideo Yagita,
Hisaya Akiba,
Margaret J. Dallman,
Paul K. H. Tam
Publication year - 2002
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/00007890-200207150-00024
Subject(s) - cd28 , transplantation , immunology , flow cytometry , t cell , medicine , immune system
The CD134/CD134L interaction provides a strong costimulatory signal that is CD28-independent. The CD134/CD134L pathway has been studied in inflammatory, autoimmune diseases, and graft-versus-host disease, but no information exists on the involvement of CD134/CD134L interactions in solid organ transplantation.