Open AccessLiver repopulation after cell transplantation in mice treated with retrorsine and carbon tetrachloride1
Author(s) -
Danqing Guo,
Tao Fu,
Jeffery A. Nelson,
Riccardo Superina,
Humberto E. Soriano
Publication year - 2002
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/00007890-200206150-00020
Subject(s) - repopulation , transplantation , carbon tetrachloride , biology , cell , andrology , cell cycle , cell division , cell growth , microbiology and biotechnology , immunology , chemistry , stem cell , medicine , biochemistry , haematopoiesis , organic chemistry
Efficiency of engraftment after liver cell transplantation is less than 1% under conventional conditions. Our aim was to develop a high-efficiency, nonsurgical, no-genetic-advantage mouse model of liver repopulation with transplanted cells.