Open AccessDNA sequencing of viral capsid protein VP-1 region in patients with BK virus interstitial nephritis
Author(s) -
Parmjeet Randhawa,
K. Khaleel-Ur-Rehman,
Patricia A. Swalsky,
Abhay Vats,
Velma P. Scantlebury,
Ron Shapiro,
Sydney Finkelstein
Publication year - 2002
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/00007890-200204150-00013
Subject(s) - capsid , genotype , bk virus , virology , biology , virus , polyomavirus infections , dna sequencing , nucleic acid sequence , genetics , dna , gene , kidney , kidney transplantation
Mutations in the viral capsid protein VP-1 region are associated with increased pathogenicity of polyomavirus in experimental systems. This study sought to determine whether analogous viral genetic changes occur in human BK virus (BKV) interstitial nephritis (ISN).