Open AccessTHE IMMUNE RESPONSE TO CORNEAL ALLOGRAFT REQUIRES A SITE-SPECIFIC DRAINING LYMPH NODE1
Author(s) -
Jarka Plskova,
Linda Duncan,
Vladimı́r Holáň,
Martin Filipec,
Georg Kraal,
John V. Forrester
Publication year - 2002
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/00007890-200201270-00010
Subject(s) - spleen , lymph node , corneal transplantation , immune system , lymph , medicine , priming (agriculture) , immune tolerance , transplantation , immunology , pathology , surgery , biology , botany , germination
Recent studies have shown that head-neck draining lymph nodes (DLN) are required for priming the immune response during corneal allograft rejection. In this study we have investigated further the role of the DLN and spleen in corneal graft rejection in mice.